Ordinary Adjustment | SOLACTIVE PHARMA & BIOTECH OPPORTUNITY INDEX | May 2019

In the ordinary index rebalance, the following changes will be implemented:

ALKERMES PLC
BIOMARIN PHARMACEUTICAL INC
EMERGENT BIOSOLUTIONS INC
GALAPAGOS NV
ARENA PHARMACEUTICALS INC
EXELIXIS INC
IPSEN SA
NEKTAR THERAPEUTICS
SWEDISH ORPHAN BIOVITRUM AB
PTC THERAPEUTICS INC
AGIOS PHARMACEUTICALS INC
HORIZON PHARMA PLC
SUPERNUS PHARMACEUTICALS INC
CHINA TRADITIONAL CHINESE MEDICINE HOLDINGS CO LTD
CHINA MEDICAL SYSTEM HOLDINGS LTD
ONO PHARMACEUTICAL CO LTD ORD
SAWAI PHARMACEUTICAL CO LTD ORD
BLUEBIRD BIO INC
BTG PLC
HIKMA PHARMACEUTICALS PLC
JAZZ PHARMACEUTICALS PLC
SINOPHARM GROUP CO LTD
SINO BIOPHARMACEUTICAL LTD ORD
3SBIO INC
LUYE PHARMA GROUP LTD
CHINA BIOLOGIC PRODUCTS HOLD
LIGAND PHARMACEUTICALS INC
MEDPACE HOLDINGS INC
SYNEOS HEALTH INC
SANTEN PHARMACEUTICAL CO LTD ORD