Acquisition | OSIRIS THERAPEUTICS INC | 18th April 2019

Due to the acquisition of OSIRIS THERAPEUTICS INC by SMITH & NEPHEW PLC, the following treatment will be applied to the following indices:

Solactive US Broad Market Index
Solactive US Extended Broad Market Index
Solactive US Small Cap Index
Solactive US Small & Mid Cap Index

• OSIRIS THERAPEUTICS INC will be removed from the Index.
• The weight of OSIRIS THERAPEUTICS INC based on its last close price will be distributed pro rata to remaining Index constituents.
• Effective Date (open): 04/18/2019.