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Ordinary Rebalance | Solactive United States Biotechnology Index | Effective Date 18th December 2023

In the ordinary rebalance, the following composition will be implemented effective open 18.12.2023:

10X GENOMICS INC
23ANDME HOLDING CO
4D MOLECULAR THERAPEUTICS INC
89BIO INC
ABCELLERA BIOLOGICS INC
ABIVAX SA-ADR
ACADIA PHARMACEUTICALS INC
ACELYRIN INC
ADAPTIVE BIOTECHNOLOGIES CORP
ADMA BIOLOGICS INC
AEROVATE THERAPEUTICS INC
AGENUS INC
AGIOS PHARMACEUTICALS INC
AKERO THERAPEUTICS INC
ALECTOR INC
ALKERMES PLC
ALLOGENE THERAPEUTICS INC
ALLOVIR INC
ALNYLAM PHARMACEUTICALS INC
ALPINE IMMUNE SCIENCES INC
AMARIN CORPORATION PLC -ADR
AMBRX BIOPHARMA INC
AMGEN INC
AMICUS THERAPEUTICS INC
AMPHASTAR PHARMACEUTICALS INC
AMYLYX PHARMACEUTICALS INC
AN2 THERAPEUTICS INC
ANAPTYSBIO INC
ANAVEX LIFE SCIENCES CORP
ANI PHARMACEUTICALS INC
APELLIS PHARMACEUTICALS INC
APOGEE THERAPEUTICS ORD
ARBUTUS BIOPHARMA CORP
ARCELLX INC
ARCTURUS THERAPEUTICS HOLDINGS INC
ARDELYX INC
ARGENX SE – ADR
ARROWHEAD PHARMACEUTICALS INC
ARS Pharmaceuticals Inc
ARVINAS INC
ASCENDIS PHARMA A/S
ASTRAZENECA PLC-SPONS ADR
ATEA PHARMACEUTICALS INC
AURA BIOSCIENCES INC
AURINIA PHARMACEUTICALS INC
AUTOLUS THERAPEUTICS PLC
AVADEL PHARMACEUTICALS PLC
AVID BIOSERVICES INC
AVIDITY BIOSCIENCES INC
AXSOME THERAPEUTICS INC
BEAM THERAPEUTICS INC
BEIGENE LTD-ADR
BELITE BIO INC – ADR
BICYCLE THERAPEUTICS LTD-ADR
BIO-TECHNE CORP
BIOCRYST PHARMACEUTICALS INC
BIOGEN INC
BIOMARIN PHARMACEUTICAL INC
BIOMEA FUSION INC
BIONTECH SE
BLUEBIRD BIO INC
BLUEPRINT MEDICINES CORP
BRIDGEBIO PHARMA INC
CABALETTA BIO INC
CARGO THERAPEUTICS ORD
CARIBOU BIOSCIENCES INC
CARTESIAN THERAPEUTICS INC
CASSAVA SCIENCES INC
CATALYST PHARMACEUTICALS INC
CELLECTIS SA
CENTESSA PHARMACEUTICALS-ADR
CEREVEL THERAPEUTICS HOLDINGS INC
COGENT BIOSCIENCES INC
COHERUS BIOSCIENCES INC
COLLEGIUM PHARMACEUTICAL INC
COMPASS PATHWAYS PLC
CONDUIT PHARMACEUTICALS INC
CORCEPT THERAPEUTICS INC
CRINETICS PHARMACEUTICALS INC
CRISPR THERAPEUTICS AG
CRONOS GROUP INC
CULLINAN ONCOLOGY INC
CUREVAC BV
CYMABAY THERAPEUTICS INC
CYTOKINETICS INC
DAY ONE BIOPHARMACEUTICALS I
DECIPHERA PHARMACEUTICALS INC
DENALI THERAPEUTICS INC
DISC MEDICINE INC
DYNAVAX TECHNOLOGIES CORP
DYNE THERAPEUTICS INC
EDGEWISE THERAPEUTICS INC
EDITAS MEDICINE INC
ENLIVEN THERAPEUTICS INC
ENTRADA THERAPEUTICS INC
ERASCA INC
EVOLUS INC
EXELIXIS INC
EYEPOINT PHARMACEUTICALS INC
FATE THERAPEUTICS INC
FENNEC PHARMACEUTICALS INC
FULCRUM THERAPEUTICS INC
GALAPAGOS NV SPONSORED ADR
GENELUX CORP.
GENMAB A/S
GERON CORP
GH RESEARCH PLC
GILEAD SCIENCES INC
GRACELL BIOTECHNOLOGIES INC
GRIFOLS SA-ADR
HALOZYME THERAPEUTICS INC
HARMONY BIOSCIENCES HOLDINGS INC
HARROW INC
HILLEVAX INC
HUMACYTE INC
HUTCHISON CHINA MEDITECH-ADR
Icosavax Inc
IDEAYA BIOSCIENCES INC
IGM BIOSCIENCES INC
ILLUMINA INC
IMMATICS N.V.
IMMUNITYBIO INC
IMMUNOCORE HOLDINGS PLC
IMMUNOGEN INC
IMMUNOVANT INC
INCYTE CORP
INHIBRX INC
INNOVIVA INC
Inozyme Pharma Inc
INSMED INC
INTELLIA THERAPEUTICS INC
INTRA-CELLULAR THERAPIES INC
IONIS PHARMACEUTICALS INC
IOVANCE BIOTHERAPEUTICS INC
IRONWOOD PHARMACEUTICALS INC
Iteos Therapeutics Inc
JANUX THERAPEUTICS INC
JAZZ PHARMACEUTICALS PLC
KALVISTA PHARMACEUTICALS INC
KARUNA THERAPEUTICS INC
KEROS THERAPEUTICS INC
KINIKSA PHARMACEUTICALS-A
KORRO BIO INC
KRYSTAL BIOTECH INC
KURA ONCOLOGY INC
KYMERA THERAPEUTICS INC
LEGEND BIOTECH CORP
LEXEO THERAPEUTICS INC
LEXICON PHARMACEUTICALS INC
LIANBIO-ADR
LIFECORE BIOMEDICAL INC
LIGAND PHARMACEUTICALS INC
LIQUIDIA TECHNOLOGIES INC
LYELL IMMUNOPHARMA INC
MACROGENICS INC
MADRIGAL PHARMACEUTICALS INC
MANNKIND CORP
MARAVAI LIFESCIENCES HOLDINGS INC
MARINUS PHARMACEUTICALS INC
MaxCyte Inc
MEIRAGTX HOLDINGS PLC
MEREO BIOPHARMA GROUP PLC
MERUS BV
MINERALYS THERAPEUTICS ORD
MIRATI THERAPEUTICS INC
MIRUM PHARMACEUTICALS INC
MODERNA INC
MOONLAKE IMMUNOTHERAPEUTICS
MORPHIC HOLDING INC
MORPHOSYS AG
NATURES SUNSHINE PRODS INC
NEUMORA THERAPEUTICS ORD
NEUROCRINE BIOSCIENCES INC
NEWAMSTERDAM PHARMA CO NV
NOVAVAX INC
NURIX THERAPEUTICS INC
Nuvalent Inc
OLEMA PHARMACEUTICALS INC
OLINK HOLDING AB – ADR
ORCHARD THERAPEUTICS PLC
ORIC PHARMACEUTICALS INC
PACIRA BIOSCIENCES INC
PETIQ INC
PHARVARIS BV
PHATHOM PHARMACEUTICALS INC
PLIANT THERAPEUTICS INC
POINT BIOPHARMA GLOBAL INC
POSEIDA THERAPEUTICS INC
PRECIGEN INC
PRIME MEDICINE INC
PROTAGONIST THERAPEUTICS INC
PROTHENA CORP PLC
PTC THERAPEUTICS INC
RAPT THERAPEUTICS INC
RAYZEBIO ORD
REGENERON PHARMACEUTICALS
REGENXBIO INC
RELAY THERAPEUTICS INC
Reneo Pharmaceuticals Inc
REPARE THERAPEUTICS INC
REPLIGEN CORP
REPLIMUNE GROUP INC
REVANCE THERAPEUTICS INC
REVOLUTION MEDICINES INC
RHYTHM PHARMACEUTICALS INC
ROCKET PHARMACEUTICALS INC
ROIVANT SCIENCES LTD
ROYALTY PHARMA PLC- CL A
RXRX.OQ
SAGE THERAPEUTICS INC
SANA BIOTECHNOLOGY INC
SANOFI-ADR
SAREPTA THERAPEUTICS INC
SAVARA INC
SCHOLAR ROCK HOLDING CORP
SEAGEN INC
SIGA TECHNOLOGIES INC
SOLENO THERAPEUTICS INC
SPRINGWORKS THERAPEUTICS INC
SUMMIT THERAPEUTICS PLC
SUPERNUS PHARMACEUTICALS INC
SYNDAX PHARMACEUTICALS INC
TANGO THERAPEUTICS INC
TARSUS PHARMACEUTICALS INC
TAYSHA GENE THERAPIES INC
TERNS PHARMACEUTICALS INC
TG THERAPEUTICS INC
THERAVANCE BIOPHARMA INC
THIRD HARMONIC BIO INC
TOURMALINE BI INC
TRAVERE THERAPEUTICS INC
TWIST BIOSCIENCE CORP
ULTRAGENYX PHARMACEUTICAL INC
UNIQURE B.V.
UNITED THERAPEUTICS CORP
UROGEN PHARMA LTD
VANDA PHARMACEUTICALS INC
VAXCYTE INC
VERA THERAPEUTICS INC
VERICEL CORP
VERONA PHARMA PLC – ADR
VERTEX PHARMACEUTICALS INC
VERVE THERAPEUTICS INC
VIATRIS INC
VIKING THERAPEUTICS INC
VIR BIOTECHNOLOGY INC
VIRIDIAN THERAPEUTICS INC
VOYAGER THERAPEUTICS INC
WALGREENS BOOTS ALLIANCE INC
WAVE LIFE SCIENCES PTE LTD
XENCOR INC
XENON PHARMACEUTICALS INC
XERIS BIOPHARMA HOLDINGS INC
Y-MABS THERAPEUTICS INC
ZAI LAB LTD
ZENTALIS PHARMACEUTICALS INC
ZYMEWORKS INC